In many cases, everything seems normal with both the man and woman, but they are still not able to conceive. In such a scenario detailed analysis need to be done, so that the cause can be identified. Testicular biopsy is one such test, where tissue samples are taken from the testicles and are analysed by laboratory experts so that they can determine problems concerning its functions. Often, a testicular biopsy is conducted to find the cause of low sperm count or other hormonal imbalances.

When is it recommended?

A testicular biopsy is usually recommended post sperm analysis. The objective of this test is to identify the cause of low sperm levels in case the sperm analysis fails to do so. In certain cases, a blockage in the testicles may be causing fertility problems which can be spotted and treated with the help of a biopsy. Also, patients undergoing IVF treatments may be required to take this test in order to retrieve sperm for intracytoplasmic sperm injection (IVF-ICSI).

How is it done?

Testicular biopsy can be conducted following either of the two procedures;

  • Open biopsy uses a surgical approach and needs to make an incision to take a tissue sample
  • Percutaneous biopsy, on the other hand inserts a needle with a syringe on the instrumental end. The syringe collects the tissue without an incision.

How is the test beneficial?

The results may show the rate of sperm development, blockages, abnormal growth, etc. In case of a normal sperm development the problem maybe a blockage which obstructs the path of the sperm on its way to the urethra. If the problem is due to sperm development the test will be able to identify it through this biopsy. On the basis of the results, treatment plans are made according to the patient. In most cases, after treatment the patient is able to conceive via assisted reproduction methods – IUI, IVF, ICSI.

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