IVF
Ovarian stimulation

What is it?

Ovarian Stimulation involves oral or injectablemedications that are given to the wife to stimulate the ovaries to produce follicles. To ensure safety, we monitor follicular growth and hormone levels using vaginal ultrasounds and blood tests.

Who is it for?

Women who have problems in egg production to stimulate the growth of follicles, to improve the chances of pregnancy.

Hysteroscopy

The role of hysteroscopy in infertility investigations is to identify possible intrauterine changes that could interfere with implantation and/or embryo growth. Hysteroscopy has been proved to be the definite method for evaluation of the uterine cavity anddiagnose associated abnormalities. It allows complete, accurate identification of intrauterineabnormalities that may negatively affect endometrial receptivity and implantation.

So even in patients with normal test results of other tests, the IVF doctor might recommend additional hysteroscopy during IVF treatment.

What is hysteroscopy ?
Hysteroscopy is a procedure that allows the doctor to look inside the womb (uterus). It is performed to assess a woman with infertility, recurrent miscarriage or abnormal uterine bleeding. Hysteroscopy can be either diagnostic or operative.
How is hysteroscopy done?

For this procedure a thin telescope-like instrument – the so called hysteroscope – is inserted through the vagina and cervix into the cavity of the womb (endometrial cavity). Skin incision is not required for hysteroscopy. After the hysteroscope is inserted through the cervix and into the uterus, sterile saline solution is injected into the uterus through the hysteroscope. This fluid expands the uterine cavity and enables the physician to directly view the inside structure of the uterus. In most cases, this procedure can be done without anaesthesia or sedation. There might be some slight cramping like period pain. Of course this procedure could be done also with anaesthesia, if required.

In case, hysteroscopy will be recommended, you will receive more detailed information and explanation by your IVF doctor.

Cryopreservation/Vitrification: Oocyte

What is it?

Vitrification is a process of preservation of oocytes (egg) by treating them with cryoprotectants(solutions that will protect the integrity of the oocytes whilst frozen) and submerging them in liquid nitrogen at a temperature of -196°C. The advantage of this procedure is that no ice crystals are allowed to form, which can damage the oocytes. Vitrification has very high survival rate of cells and delivers excellent clinical results.

What benefits does it offer?

In case of surplus oocytes retrieved in an IVF cycle, the oocytes can be vitrified and stored for up to 5 years. So later on, another stimulation cycle might be avoided and pregnancy can be achieved by using the previously frozen oocytes.

Another field where vitrification is helpful is in becoming a mother after receiving cancer therapy. The vitrification of oocytes is today the most viable option for the preservation of fertility in women who requirechemotherapy or radiotherapy treatments.

Blastocyst Culture

What is it?

A blastocyst is an embryo that has developed for five or six days after fertilisation. Usually in IVF, embryos are transferred to the uterus after 48 or 72 hours, but in natural conception, the embryo reaches the uterine cavity only on the fifth day. Blastocyst culture is a procedure where embryos are grown in the laboratory till the blastocyst stage. This allows embryologists to select the best embryo forimplantation and hence transfer far better and far fewer embryos. This lowers the risk of multiple pregnancies while ensuring high pregnancy rates. A longer time in culture provides an opportunity to conduct Preimplantation Genetic Screening (PGS) or Preimplantation Genetic Diagnosis (PGD) to check for chromosomal and genetic abnormalities.

Laser Assisted Hatching

What is it?

Laser assisted hatching is a procedure used along with IVF-ICSI to improve the embryo?s chances of implantation. The principal concept behind this procedure is to assist the embryo?s escape from the outer shell, so that it can implant into the mother?s uterine wall. Since Laser Assisted Hatching is delicate and complicated, it must be done by highly trained and experienced embryologists.

Who is it for?

Women with advanced age or thick zona (outer shell of embryo).

Embryoscope

What is it?

An embryoscope is an advanced IVF incubator with a built-in time-lapse camera. It enables embryologists to keep a close watch on the development of embryos in a safe environment – from fertilisationuntil the transfer back into the uterus. This allows selection of the best embryos for transfer and has helped enhance pregnancy rates in IVF cycles.

How does it help?

It helps embryologists track embryo growth and identify abnormalities.

It improves the embryo selection process.

It enhances pregnancy rates in IVF cycles by as much as 17%.

Improves the culturing conditions and the handling of the embryo.

Andrology services: Helping men overcome fertility issues

We offer comprehensive andrology services including evaluation and treatment of the husband for infertility or sexual problems.

Detailed semen analysis

Semen analysis is the most important test for assessing male fertility. The count, motility (activity) and morphology (structure) of the sperm in the semen gives valuable information on whether a man has impaired fertility.

Testicular Sperm Aspiration (TESA)

In men with azoospermia (no sperm found in the semen sample), Testicular Sperm Aspiration (TESA) is a procedure for retrieval of sperm for ICSI. The process involves inserting a needle through the testicle under local anaesthesia and aspirating tissue/sperm. TESA is performed for men with obstructive azoospermia and other cases of advanced infertility issues.

Micro Testicular Sperm Extraction (Micro TESE)

Micro TESE is an advanced andrological procedure

performed on male patients diagnosed with extreme male infertility and in cases where TESA is not successful. The process involves an operation performed through a small incision in the scrotum. The testicle is then examined under a microscope for dilated testicular tissues that are more likely to contain sperm. These areas are collected and examined for good quality sperm. This process is repeated in different areas till sperms of optimum quality are discovered. Patients who have undergone previous testicular surgery, previous medical treatment or have genetic problems will find Micro TESE immensely helpful.

Compatibility Genetic Testing (CGT)

What is it?

CGT allows genetic testing of a couple beforepregnancy to promote the birth of a healthy baby. It will provide information regarding the risk of having a child with a genetic disorder as the test will reveal whether the prospective parents are carriers of any genetic mutations.

Who is it for?

Prior to an assisted reproduction treatment: It is advised in order to determine the risk of transmission so that the best type of treatment can be decided on in each case.

Before trying to become pregnant naturally: For any woman who wants to become pregnant, so that she knows the risk of passing on possible diseases to her child

Preimplantation Genetic Screening (PGS)

What is it?

Preimplantation genetic screening involves checking all 46 chromosomes of embryos conceived via In-Vitro Fertilisation or Intra Cytoplasmic Sperm Injection for common abnormalities. This decreases the possibility of abnormal embryos being transferred to the uterus during IVF or ICSI.

Who is it for?

Patients over 35 years of age who have a higher risk of having a baby with chromosome problems (such as Down′s Syndrome).

Patients with recurrent miscarriages or several unsuccessful cycles of IVF.

If the male partner?s sperm shows a high risk of chromosome problems.

Preimplantation Genetic Diagnosis (PGD) for Single Gene Disorders

What is it?

Preimplantation genetic diagnosis is the diagnosis of specific genetic conditions prior to pregnancy. PGD can diagnose chromosomal aneuploidy/rearrangements and single gene disorders. PGD can benefit any couple at risk of passing on a genetic disease or condition.

Who is it for?

Couples at risk of transmitting chromosomal alterations or monogenic diseases.

Couples with a clinical history of repeated abortions or miscarriages.

Women with implantation failure after several attempts with IVF.

Alterations in the meiosis of the spermatozoa.

Women of advanced age.

Endometrial Receptivity Array (ERA)

What is it?

Endometrial receptivity array involves assessing a woman?s endometrial receptivity status from a molecular viewpoint, meaning that it determines whether the lining of the uterus (Endometrium) is ready to accept the embryo. Thismolecular tool allows diagnosis of whether the endometrium is receptive or not, by analysing the expression of a group of genes responsible for this function. With the endometrial gene expression diagnosis, problems that may affect the embryo implantation can be detected before starting the fertility treatment. As a result, corresponding measures can be taken to carry out the fertilitytreatment successfully

Who is it for?

Patients with repeated IVF failures.

Products of Conception using Array CGH (POC)

What is it?

This is a test to identify the cause of pregnancy loss. It is conducted using Array CGH technology. It enables the study of all the chromosomes to detect aneuploidies in foetal tissue. Aneuploidies are chromosomal abnormalities which account for more than 50% of first trimester pregnancy losses.

Who is it for?

Couples who have suffered a pregnancy loss.

Women having recurrent miscarriages.

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