Spermatogenesis is the process of spermatozoa production in the male testes. The initial stages of this process occur in a part of the testes, called the seminiferous tubules. In non-obstructive azoospermia, spermatozoa production might be restricted to few parts of the testis, mainly in the healthy tubules.

Micro-TESE procedure allows the surgeon to identify the healthy tubules depending on their appearance and diameter. This gives a better chance of finding spermatozoa, unlike the regular TESE procedure where biopsies are taken randomly from different parts of the testis.


For the Micro-TESE procedure, the male patient will be given general anaesthetic and a small cut in the skin and then in the testis is necessary in order to search for the tubules containing sperms. A high power operating microscope (20X magnification) is used to identify the dilated healthy seminiferous tubules.

The use of this technique will minimize the damage done to the testis by minimal tissue extraction, and will reduce the time required for tissue processing and spermatozoa search in the laboratory. Moreover, it is thought that the chances of finding spermatozoa will increase by micro TESE as compared to classical TESE.

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