Dr. Human Fatemi
Dr. Barbara Lawrenz
In an IVF or any other assisted reproduction method, apart from embryo quality and successful transfer a pregnancy is established only if the embryo implants on to the uterine lining. For this, the timing of the transfer needs to be right when the lining of the uterus is the most receptive to the embryo.
The endometrium or endometrial cavity is the lining in the uterus, where the fertilised egg or the embryo goes and attaches itself for growth and development during the remaining gestation period. Therefore, its receptiveness plays a crucial role in a successful pregnancy. If a woman has undergone failure in pregnancy or miscarriages, due to non-implantation of the embryo, this test can help identify the “window” in which the uterus is most likely to allow successful implantation.
The uterus is an organ in a female reproductive system where the pregnancy develops. Space inside the uterus is lined with a membrane called the endometrial tissue. This area is called the endometrium. In case of conception, this is where the embryo attaches itself and develops into a foetus during the gestation period.
When the embryo travels to the uterus, its chances of attaching itself to the endometrium depend upon the endometrium’s receptiveness. A receptive endometrium is a healthy sign that often ends in a successful pregnancy. On the other hand, a non-receptive endometrium could imply an abnormality and point at several possible problems affecting the patient.
The endometrial receptiveness array allows genome analysis marking the ‘Window of Implantation’. This is the period during which the uterus is most receptive to the embryo for implantation. The results are further analysed, and the window is marked for carrying out the IVF procedure for a successful pregnancy.
These tests are recommended when the patient has had an implantation failure either in natural or assisted conception. In case of IVF (In Vitro Fertilisation), the receptiveness of the endometrium is tested to ensure a successful implantation of the embryo(s).
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